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Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules such as renewable biofuels or anticancer drugs. However, traditional synthetic biology approaches involve ad-hoc engineering practices, which lead to long development times. Here, we present the Automated...

Structural disorder is widespread in eukaryotic proteins and is vital for their function in diverse biological processes. It is therefore highly desirable to be able to predict the degree of order and disorder from amino acid sequence. It is, however, notoriously difficult to predict the degree of...

By using R, Flexdashboard and Leaflet, we can build a customized and branded web application to showcase location based data interactively across the organization. Instead of crowding the application with many widgets, we use menu tabs and pages to separate the interactive aspects.

Metabolic processes in the human body can alter the structure of a drug affecting its efficacy and safety. As a result, the investigation of the metabolic fate of a candidate drug is an essential part of drug design studies. Computational approaches have been developed for the prediction of possible...

Brain injury is a significant source of morbidity and mortality for pediatric patients treated with Extracorporeal Membrane Oxygenation (ECMO). Our objective was to utilize neural networks to predict radiographic evidence of brain injury in pediatric ECMO-supported patients and identify specific...

A methodology for the automated identification of building damage from post-disaster aerial images was developed based on convolutional neural network (CNN) and building damage inventories. The aerial images and the building damage data obtained in the 2016 Kumamoto, and the 1995 Kobe, Japan...

The recent sale of an artificial intelligence (AI)-generated portrait for $432,000 at Christie's art auction has raised questions about how credit and responsibility should be allocated to individuals involved and how the anthropomorphic perception of the AI system contributed to the artwork's...

Computer vision models learn to perform a task by capturing relevant statistics from training data. It has been shown that models learn spurious age, gender, and race correlations when trained for seemingly unrelated tasks like activity recognition or image captioning. Various mitigation techniques...

Data science has primarily focused on big data, but for many physics, chemistry, and engineering applications, data are often small, correlated and, thus, low dimensional, and sourced from both computations and experiments with various levels of noise. Typical statistics and machine learning methods...

Conventional single-spectrum computed tomography (CT) reconstructs a spectrally integrated attenuation image and reveals tissues morphology without any information about the elemental composition of the tissues. Dual-energy CT (DECT) acquires two spectrally distinct datasets and reconstructs energy...

Engineered RNA elements are programmable tools capable of detecting small molecules, proteins, and nucleic acids. Predicting the behavior of these synthetic biology components remains a challenge, a situation that could be addressed through enhanced pattern recognition from deep learning. Here, we...

With more professionals from a wide range of less technical fields diving into statistical analysis and data modeling, these experimental techniques can seem daunting. To help with these hurdles, this article clarifies some misconceptions around p-values, hypothesis testing, and statistical...

What is an algorithm? How computers know what to do with data

Computational method for screening drug compounds can help predict which ones will work best against tuberculosis or other diseases.

System developed at MIT CSAIL aims to help linguists decipher languages that have been lost to history.

Marketing scientist Kevin Gray asks Dr. Anna Farzindar of the University of Southern California about recommender systems and the ways they are used.

Social media algorithms, artificial intelligence and our own genetics are among the factors influencing us beyond our awareness. This raises an ancient question: do we have control over our own lives? This article is part of The Conversation’s series on the science of free will.

The dynamics of CD4+ T cell memory development remain to be examined at genome scale. In malaria-endemic regions, antimalarial chemoprevention protects long after its cessation and associates with effects on CD4+ T cells. We applied single-cell RNA sequencing and computational modelling to track...

Modeling visitor engagement is a key challenge in informal learning environments, such as museums and science centers. Devising predictive models of visitor engagement that accurately forecast salient features of visitor behavior, such as dwell time, holds significant potential for enabling adaptive...